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Measuring Absolute Coronary Flow and Microvascular Resistance by Thermodilution: JACC Review Topic of the Week.
Belmonte, Marta; Gallinoro, Emanuele; Pijls, Nico H J; Bertolone, Dario Tino; Keulards, Danielle C J; Viscusi, Michele Mattia; Storozhenko, Tatyana; Mizukami, Takuya; Mahendiran, Thabo; Seki, Ruiko; Fournier, Stephane; de Vos, Annemiek; Adjedj, Julien; Barbato, Emanuele; Sonck, Jeroen; Damman, Peter; Keeble, Thomas; Fawaz, Samer; Gutiérrez-Barrios, Alejandro; Paradies, Valeria; Bouisset, Frederic; Kern, Morton J; Fearon, William F; Collet, Carlos; De Bruyne, Bernard.
Affiliation
  • Belmonte M; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium; Department of Advanced Biomedical Sciences, University Federico II, Naples, Italy.
  • Gallinoro E; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium; Cardiology Department, Galeazzi-Sant'Ambrogio Hospital, Milan, Italy.
  • Pijls NHJ; Department of Cardiology, Catharina Hospital, Eindhoven, the Netherlands. Electronic address: nico.pijls@xs4all.nl.
  • Bertolone DT; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium.
  • Keulards DCJ; Department of Cardiology, Catharina Hospital, Eindhoven, the Netherlands; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.
  • Viscusi MM; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium; Department of Advanced Biomedical Sciences, University Federico II, Naples, Italy.
  • Storozhenko T; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium.
  • Mizukami T; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium.
  • Mahendiran T; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.
  • Seki R; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium.
  • Fournier S; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.
  • de Vos A; Department of Cardiology, Catharina Hospital, Eindhoven, the Netherlands; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.
  • Adjedj J; Department of Cardiology, Institut Arnault Tzanck, Saint-Laurent-du-Var, France.
  • Barbato E; Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.
  • Sonck J; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium.
  • Damman P; Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
  • Keeble T; Essex Cardiothoracic Centre, Mid South Essex NHS Foundation Trust, Basildon, Essex, United Kingdom; Medical Technology Research Centre, Anglia Ruskin School of Medicine, Chelmsford, Essex, United Kingdom.
  • Fawaz S; Essex Cardiothoracic Centre, Mid South Essex NHS Foundation Trust, Basildon, Essex, United Kingdom; Medical Technology Research Centre, Anglia Ruskin School of Medicine, Chelmsford, Essex, United Kingdom.
  • Gutiérrez-Barrios A; Cardiology Department, Hospital Puerta del Mar, Cádiz, Spain; Instituto de Investigación e Innovación en Ciencias Biomédicas de Cádiz, Cádiz, Spain.
  • Paradies V; Department of Cardiology, Maasstad Hospital, Rotterdam, the Netherlands.
  • Bouisset F; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium.
  • Kern MJ; Veteran's Administration Long Beach Health Care System, Long Beach, California, USA.
  • Fearon WF; Department of Medicine, Division of Cardiology, Stanford Medical Center Palo Alto, Palo Alto, California, USA; VA Palo Alto Health Care System, Palo Alto, California, USA.
  • Collet C; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium.
  • De Bruyne B; Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland. Electronic address: bernard.de.bruyne@gammas.be.
J Am Coll Cardiol ; 83(6): 699-709, 2024 02 13.
Article in En | MEDLINE | ID: mdl-38325996
ABSTRACT
Diagnosing coronary microvascular dysfunction remains challenging, primarily due to the lack of direct measurements of absolute coronary blood flow (Q) and microvascular resistance (Rµ). However, there has been recent progress with the development and validation of continuous intracoronary thermodilution, which offers a simplified and validated approach for clinical use. This technique enables direct quantification of Q and Rµ, leading to precise and accurate evaluation of the coronary microcirculation. To ensure consistent and reliable results, it is crucial to follow a standardized protocol when performing continuous intracoronary thermodilution measurements. This document aims to summarize the principles of thermodilution-derived absolute coronary flow measurements and propose a standardized method for conducting these assessments. The proposed standardization serves as a guide to ensure the best practice of the method, enhancing the clinical assessment of the coronary microcirculation.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocardial Ischemia / Coronary Circulation Type of study: Guideline Limits: Humans Language: En Journal: J Am Coll Cardiol Year: 2024 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocardial Ischemia / Coronary Circulation Type of study: Guideline Limits: Humans Language: En Journal: J Am Coll Cardiol Year: 2024 Document type: Article Affiliation country: Country of publication: